PICC Lines:
care, covers, tips + more

by Mighty Well


What to Expect with Your First PICC Line

Your first PICC line (Peripherally Inserted Central Catheter) you will likely come with a bunch questions. Do you want to know what to expect during the procedure and in your first days home? Don’t worry, Mighty Well has you covered! Here’s what to expect from your first PICC line.

What happens during PICC line placement?

Any new medical intervention comes with some fears. The best way to calm these fears is to learn as much as you can ahead of time!  

PICC line placement is no different — the more you know, the more confident you will feel walking into the procedure.  A PICC line (peripherally inserted central catheter) is a thin tube inserted through the veins in your arm into larger veins near your heart. It is often used when patients need frequent IV treatments, to minimize pain and damage to the veins from frequent needles.  

We know how it feels to be facing this type of procedure, so we’ve put together a list of what to expect.

PICC vs. Port

Is it time to decide which medical device is right for you? There are a lot of reasons why patients may need to get a peripheral catheter inserted. Sometimes patients are given the option to choose between a PICC line and a Port, but before making your big decision, it’s important to know the facts about both medical devices.

PICC line vs. central line: weighing your options

Vascular Access refers to the delivery of fluids and medication through the bloodstream. PICCs and Central Lines are two methods of vascular access. Learn the difference between the two, and what are the pros and cons of choosing one versus the other.

4 Ways to Prepare for a PICC Placement

Going into a medical procedure is always a little scary. The best way to minimize fear and anxiety is to go in as prepared as you can! If you are feeling nervous for an upcoming PICC line placement procedure, here are some confidence boosting tips for feeling ready to go.

What patients want to know to feel confident about their PICC line

Starting out with your first PICC can be nerve-wracking. Patients need to grapple with a slew of emotions, acceptance that a visible medical device is necessary, and the anxiety that often accompanies new procedures. Providers can make a word of difference by helping patients feel confident going into the procedure. We’ve chatted with patients and providers about what information is the most helpful before procedure day.

caring for your PICC line during COVID-19

This is a tough time to have a PICC line. You may already be immunocompromised, and PICC lines add a significant risk of infection. Hospitals are overloaded and breaking quarantine to take care of an unplanned PICC line problem adds risk of picking up COVID-19.

The good news is that how you take care of your PICC can make a world of difference! We have asked our Friends in the Fight, over the years, for their tips and tricks

caring for your PICC line: our top 4 tips

Any medical device comes with risks and fears. PICC lines, while safer alternatives for those needing frequent IV treatments, do come with risk of complications.

The good news is that how you take care of your PICC can make a world of difference! We have asked our Friends in the Fight, over the years, for their tips and tricks.

patient tips: how to shower with a PICC line

When you have a PICC line, life is already hard. You have to remember to organize and prep your medication, set up your nursing visits, and to take the time to do your infusions. As this wasn’t enough, one of the biggest challenges becomes showering. Here are our 4 most commonly asked questions for showering with a PICC line answered by our very own professional patient.

how to change your PICC line dressing

In the days after I first got my PICC Line inserted, I was obsessed with making sure it was clean and free from infection. Though we had regularly scheduled visits from home nurses, my Dad and I made it our mission to learn how to complete a PICC Line dressing change so that no matter what happened, we would be able to keep the site clean, secure, and protected.

Those first few days were scary and I was so grateful to my dad for taking the time to learn how to learn this process. I quickly learned that together, we could complete a PICC Line dressing change like pros.

Here are a few important tips for managing your PICC Line Dressing change at home.

two PICC line complications to watch out for

PICC lines are a modern medical device that are commonly used for patients who are in need of intravenous therapy over a long period. Unlike standard IVs which can only be used for a short period of time and can cause damage or scarring to the veins after repeated insertions, a PICC line goes in once (with careful insertion) and can remain for as long as 12 months. Nurses and doctors today have a lot of experience with them, however PICC lines have their own risks. With guidance and proper care, these can be minimized.

PICC line complications: common issues and how to prevent them

If you’ve been recently diagnosed to require a PICC line, it can be overwhelming. To avoid PICC line complications, it’s important to know how to take care of yourself while wearing a PICC line, such as keeping it clean and hygienic with PICC line dressing changes.

7 things not to do with a PICC line

Having a PICC line on your upper arm is no fun, but you can still manage tasks you need to accomplish without complications. A PICC line should not hinder you from the normal activities you enjoy. It takes a lot of getting used to, but it is worth it.

So many people wonder how to care and maintain it. It could be tough wearing this piece of catheter for most of us. To be more comfortable with your PICC line, discover some of the best ways to help patients who have this long, flexible tube in their arm.

4 Tips For Reducing PICC Line Pain

Getting a PICC line (Peripherally Inserted Central Catheter) means opening yourself up to new treatment options and healing! It can also feel scary. Patients often ask us if PICC lines will hurt and, if so, how to best reduce the pain. The answer is complicated. Everyone is different, and every PICC placement is different.

If you do find yourself in pain, there’s no need to panic — it may be perfectly normal and short-lived. We’ll help you navigate the different types of pain and share some tips we’ve found for making it feel better. Please remember, however, that we are not medical professionals, and you should always call your doctor if concerned.

Experiencing PICCPerfect® With Skin Sensitivities

PICC lines come with a lot of baggage. There’s the emotional weight of having a medical condition, plus the stigma of having a visible medical device. Then there’s the increased likelihood of pain and sensitivities that can come with illness, not to mention the wear-and-tear of adhesives on your skin. It’s times like these when comfort becomes crucial.

5 Tips for Staying Safe With Chronic Illness as the World Opens Up

What is deemed safe by some may not be safe for all. As the world begins to venture out again, we all need to take stock of what we need to feel safe, and respect the boundaries of those around us.

If you’re feeling nervous about re-opening, you’re far from alone! “Re-opening anxiety” has become a new buzzword among psychology experts. The good news is that by getting yourself prepared now, you can keep yourself safe — physically and emotionally — when it comes time to ease back into your old way of life.

3 Tips for Coping With Cognitive Dysfunction

While symptoms can vary from one illness to another, one symptom is almost universal to the chronic illness experience: brain fog. Also called cognitive dysfunction, brain fog can be caused by neurological issues or even just the fatigue and stress of being sick for long periods of time. It often feels like a thick fog slowing your thoughts and reactions, but it can come in many forms.

5 Tips for Chronic Pain

Living with chronic pain is exhausting. It’s so much more than just the sensation of pain — it’s the part of your brain that’s constantly distracted, it’s the painsomnia from not being able to get comfortable at night, the grief of giving up activities made impossible, the emotional toll of trying to push through and act normal, and the isolation of existing in such a different space than the people around you.

Perhaps none of this will be new for you, but here you’ll find some tips that have worked for many of Friends in the Fight.

COVID-19: 5 tips for navigating an outbreak with chronic illness

As COVID-19 and fears around coronavirus spread around the world, many members of our community are at the highest risk for infection. Being immunocompromised during cold and flu season is already stressful enough, and the global spread of a highly infectious virus adds significant anxiety for our Friends in the Fight, as well as the need for further precaution.

If you are feeling additional stress during this uncertain time, Mighty Well and your Friends in the Fight are here to support you as you make decisions about how to best manage your health and wellbeing. If you are looking for support or more tips from our Friends in the Fight community, join our Facebook Group!

Here are five chronic illness specific tips for navigating the COVID-19 outbreak:


Get the patient approved PICCPerfect®

Life changing for any PICC users

Favorite PICC line cover!

PICCPerfect Antimicrobial PICC Line Cover By Mighty Well

PICCPerfect®: Antimicrobial PICC Line Covers

The PICCPerfect® PICC Line Cover protects and covers your PICC Line and brings dignity and comfort to your day! Patent No. D818120.

Functional Design: Double access points make it easy to access single and double lumens without exposing your PICC Line insertion site. The access points are bonded through a heating process (so no itchy stitching or thread!).

Antimicrobial and Soft-touch Fabric: Advanced fabric technology including antimicrobial, moisture-wicking and anti-odor properties for every kind of adventure.

Eco-friendly, Improved Recovery & Bright Patterns: Our unique fabric is recycled from coffee beans to lessen our environmental impact.

Concealing: We know how sensitive your skin can get every time your nurse needs to change your dressing; with our PICC Line Cover's two-layer design, your PICC does not have to touch your skin!

Bonded anti-slip edges prevent the cover from slipping down your arm.

This product is HSA & FSA eligible!


Keep your PICCPerfect® looking 100%

don't get it wet

Don’t use your PICCPerfect® for bathing or showering.
Use a waterproof PICC Protector.

keep it clean

The recommended use is 2 days. When at home, please wash your PICCPerfect® in a machine washer and tumble dry on normal-low heat. Use another PICCPerfect® while the first one is in the wash. We offer a discount if you buy multiple!

give it a rest

If your PICCPerfect® is falling down your arm even after washing and drying, you might be using a size too big. You can exchange it for a smaller size. At night, lay the PICCPerfect® that you're not wearing that day flat. This gives the spandex a chance to relax and reshape.

finding your size:

what is your PICCPerfect® size?

Measure around your bicep where your PICC line is placed. See the size guide below to select your size. If you are in between two sizes, select the smaller size.

xxxs xxs xs s m l xl








FIT: The PICCPerfect® is designed to have a snug and comfortable fit around your arm. If your PICC line cover is slipping down your arm, even after following care instructions, you should be wearing a smaller size. For help with a size exchange, send us a text at 617-804-1837.

how to's:

how to check on/visualize the PICC line insertion site:

Fold the OUTER section of PICCPerfect® down to show the PICC line. Then, fold the INNER section just enough to visualize the PICC line insertion site.

how to remove PICCPerfect®:

1. Fold the OUTER section of PICCPerfect® down to expose the PICC line.
2. Fold INNER section to visualize the PICC.
3. Gently, pull the lumen(s) out one at a time, and pull the device down your arm.


  • When at home, the suggested use of PICCPerfect® is 2-3 days before washing.
  • DO NOT use PICCPerfect® for bathing or showering. The PICCPerfect® is NOT waterproof.
  • DO NOT fold or pull down PICCPerfect® with force or quick movement.
  • DO NOT remove PICCPerfect® without bringing the lower section down first.
  • DO NOT put on PICCPerfect® without using a sterile dressing or changing on the site.


Got more questions about PICC Lines?

Join us in our Friends in the Fight Group to connect with our community.

Sign Up For Our Newsletter

Be in the know on our latest product launches, exclusive offers, and tips for Living Mighty Well!